Publications
Selected landmark and recent work
Explore work on p53 mRNA, DNA-damage signaling, synonymous variants, mutant p53 and evolutionary cancer protection.
A cancer-associated TP53 synonymous mutation induces synthesis of the p53 isoform p53/47
British Journal of Cancer
The p53 mRNA exhibits riboswitch-like features under DNA damage
iScience
Thermal stress, p53 structures and learning from elephants
Cell Death Discovery
The DNA damage sensor ATM kinase interacts with histone variant H2AX
Nature Communications
The Elephant Evolved p53 Isoforms that Escape MDM2-Mediated Repression and Cancer
Molecular Biology and Evolution
Targeting Oncogenic Pathways in the Era of Personalized Cancer Therapy
Cancers
What do we need to know and understand about p53 to improve its clinical value?
Journal of Pathology
Molecular and Biochemical Techniques for Deciphering p53–MDM2 Signaling
Biomolecules
A single synonymous mutation determines the phosphorylation and stability of the nascent protein
Journal of Molecular Cell Biology
Shaping the regulation of the p53 mRNA tumour suppressor
BMC Cancer
The p53 mRNA: an integral part of the cellular stress response
Nucleic Acids Research
p53 mRNA and p53 Protein Structures Have Evolved Independently to Interact with MDM2
Molecular Biology and Evolution